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Hello! I'm Sam


In addition to my research activity, I enjoy supervising students in biomedical research topics and teaching mathematics. I am active in numerous associations, and currently serve as a board member for the Society of Mathematical Biology and a Science Policy Fellow for the Society of Industrial and Applied Mathematics. In my spare time, I compete in equestrian competitions and am on the board of directors for New Life Center for Thoroughbreds.


Samantha Erwin, PhD

Applied Mathematics, Computational Biology, Infectious Diseases



(859) 414-2789





Oak Ridge National Laboratory

Oak Ridge, TN 37831

Google Scholar:

Samantha Erwin

ORNL Profile:

Sam Erwin

Sept. 2019-Present

Research & Development Associate Staff Member

Oak Ridge National Laboratory

Scientist in the Computing and Computational Sciences directorate working in the Advanced Computing for Health Sciences Section. The group uses artificial intelligence and supercomputing to solve the nation’s leading health initiatives.

I am actively recruiting undergraduates and early graduate students to participate in summer internships using artificial intelligence and machine learning for biomedical projects.

July 2017-August 2019 

Postdoctoral Research Scholar 

North Carolina State College of Veterinary Medicine

Based in Cristina Lanzas’s lab in the Population Health and Pathobiology Department. I developed mathematical models of molecular mechanisms in C. difficile infection and of antibiotic resistance using nonlinear mixed effect models.


Visiting Graduate Student 

Biocomplexity Institute of Virginia Tech

I collaborated with bench-top scientist in the Nutritional Immunology and Molecular Medicine Laboratory (NIMML) to understand the effects in an HIV and HPV coinfection. I also participated in laboratory work to gain experience in experimental protocols.

May 2017

Ph.D. Mathematics

Virginia Polytechnic Institute and State University


Dissertation Topic: “Mathematical models of immune responses to infectious diseases

June 2013

M.S. Mathematics

Virginia Polytechnic Institute and State University


Thesis Topic: “Modeling of Passive Chilled Beams for use in Efficient Control of Indoor-Air Environments”

May 2011

B.S. Mathematics 

Murray State University

Outside of academia I compete my horse a
I also enjoy hiking
In memory of my dog Chloe, who was there

[Jan 2021]

Awarded Murray State University’s Distinguished Young Alumni

[October 2020]

Named ORNL's Coordinator for the National Science Foundation's Mathematical Sciences Graduate Internship

[June 2020]

Appointed Board of Directors of New Life Center for Thoroughbreds

[Jan 2020]

Awarded the SIAM Science Policy Fellowship for 2020 - 2022

[May 2019]

Appointed Chair of the Membership Committee for the Society of Mathematical Biology.

[May 2019]

Winner of best poster at the NC State Postdoctoral Research Symposium.


S Erwin, DM Foster, ME Jacob, MG Papich, C Lanzas. Mathematical mechanistic modeling the effects of fluoroquinolones on antimicrobial susceptibility of enteric bacteria. PLOS One, 15(1): e0228138. 2020.

C Lanzas, K Davies, S Erwin, D Dawson. On modelling environmentally-transmitted pathogens. Interface Focus, 10(1), 2019.